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Tumor-Normal Paired Exome-Sequencing pipeline

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Hello,
We're currently running a research project involving exome sequencing of tumors and paired normal blood samples from brain cancer patients.
I'm relatively new to NGS processing but thanks to this forum (and the excellent documentation provided by the Broad) I was able to put together the following pipeline for this project:

I just wanted to check with the Cancer Team that everything looks OK, as well as get any suggestions, if possible.
Looking forward to your valuable response,
-E


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